Dr Bairwa from CU Jammu discover crucial links between Metabolism, Protein Degradation and Genome duplication processes

Jammu, 27 Nov 2024: Dr Narendra K Bairwa, Associate Professor and the Director, of the Centre for Molecular Biology, Central University of Jammu discovered crucial links between Metabolism, Protein Degradation and Genome duplication processes. He investigated the role of molecules (Genes) related to metabolism and DNA replication processes. These processes are conserved from the simple eukaryote organism to complex multicellular organisms. The researcher carried out a laboratory investigation using yeast, S. cerevisiae as the model organism and reported that ablation of the genes involved in the metabolism and DNA replication process impacted growth, cell size, metabolism, and DNA replication process.

An understanding of the functional role of genes and their networks is crucial in determining cellular physiology and disease understanding. Dr. Bairwa published their findings in the SCI-indexed Journal, Journal of Biochemical and Molecular Toxicology (JBMT) with the title “Genetic Interaction Between F-Box Encoding UCC1 and RRM3 Regulates Growth Rate, Cell Size, and Stress Tolerance in Saccharomyces cerevisiae” in the November 2024 issue. The published work can be accessed using the following URL ( https://doi.org/10.1002/jbt.70059). Dr. Narendra Kumar Bairwa’s laboratory studies gene-gene interactions, genome stability regulation, stress response, and screening small molecules for drug discovery. Honourable Vice-Chancellor, Central University of jammu, Prof. Sanjeev Jain congratulated the authors for carrying out the fundamental and applied research work.